New isoquinoline- carboxamide amino acid derivatives useful...

Details New isoquinoline- carboxamide amino acid derivatives useful... New isoquinoline- carboxamide amino acid derivatives useful...

C - Chemistry, Metallurgy

07

D

C07D 217/26 (2006.01) A61K 31/47 (2006.01) C07D 401/12 (2006.01) C07K 5/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2030433

Compounds of the general formula (see fig.I) wherein R represents benzyloxycarbonyl or 2-quinolylcarbonyl, and their pharmaceutically acceptable acid addition salts inhibit proteases of viral origin and can be used as medicaments for the treatment or prophylaxis of viral infections. They can be manufactured according to generally known procedures.

Composés de formule générale (voir fig. I), où R représente du benzyloxycarbonyle ou du 2-quinolylcarbonyle, et leurs sels d'addition avec un acide, acceptables en pharmacie, inhibiteurs de protéases d'origine virale et pouvant être utilisés comme médicaments pour le traitement ou la prévention des infections d'origine virale. Ils peuvent être obtenus à l'aide de procédés bien connus.

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