Pharmaceutical compositions containing cyclosporine and a...

Details Pharmaceutical compositions containing cyclosporine and a... Pharmaceutical compositions containing cyclosporine and a...

A - Human Necessities

61

K

A61K 38/13 (2006.01) A61K 47/24 (2006.01)

Patent

CA 2255640

A description is given of new pharmaceutical compositions containing cyclosporine, combined with a carrier comprising at least a derivative of .alpha.-glycerophosphoric acid, such as .alpha.-glycerophosphorylcholine, .alpha.-glycerophosphorylserine, .alpha.-glycerophosphorylethanolamine and .alpha.-glycerophosphoryl-myo-inositol, which allow cyclosporine bioavailability to significantly increase.

L'invention concerne de nouvelles compositions pharmaceutiques contenant de la cyclosporine, associée à un support comprenant au moins un dérivé d'acide .alpha.-glycérophosphorique, tel que l'.alpha.-glycérophosphorylcholine, l'.alpha.-glycérophosphorylsérine, l'.alpha.-glycérophosphoryléthanolamine et l'.alpha.-glycérophosphoryl-myo-inositol, qui augmentent significativement la biodisponibilité de la cyclosporine.

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