Novel uses of combined selective dopamine d2 receptor...

A - Human Necessities – 61 – K

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A61K 31/00 (2006.01) A61K 31/275 (2006.01) A61K 31/277 (2006.01) A61K 31/4433 (2006.01) A61P 25/18 (2006.01) A61P 25/22 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2428519

Use of compounds being combined selective dopamine D2 receptor antagonists and 5-HT1A receptor agonists, in particular (R)-(-)-2-[5-4 fluorophenyl)-3- pyridylmethyl-aminomethyl]-chromane or a physiologically acceptable salt thereof or N-(4'-fluoro-3-biphenylmethyl)-N-2-(3-cycanophenoxy-ethyl)-amine or a physiologically acceptable salt thereof, for the manufacture of a medicament for use in veterinary medicine for the treatment of self directed traumatic disorders associated with behavioral stressors, compulsive disorders associated with behavioral stressors and/or anxiety disorders associated with behavioral stressors.

L'invention porte sur l'utilisation de l'antagoniste combinés sélectif du récepteur D2 de la dopamine et de l'agoniste du récepteur de la 5-HT¿1A?, et en particulier du (R)-(-)-2-[5-4 fluorophényl)-3-pyridylméthyl-aminométhyl]-chromane ou l'un de ses sels biocompatible ou du N-(4'-fluoro-3-biphénylméthyl)-N-2-(3-cycanophénoxy-éthyl)-amine ou l'un de ses sels biocompatible, pour la fabrication d'un médicament à usage vétérinaire servant au traitement de traumatismes autodirigés associés à des stresseurs comportementaux, ou de troubles compulsifs associés aux stresseurs comportementaux, et/ou de troubles liés à l'angoisse associés à des stresseurs comportementaux.

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