Ninjurin-1 and/or mcam modulation and uses thereof

Details Ninjurin-1 and/or mcam modulation and uses thereof Ninjurin-1 and/or mcam modulation and uses thereof

A - Human Necessities

61

K

A61K 38/10 (2006.01) C12N 5/0783 (2010.01) A61K 31/713 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61P 25/00 (2006.01) A61P 29/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/567 (2006.01) C07K 7/06 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2676962

Methods, uses, agents and compositions useful for the prevention, treatment and/or diagnosis of inflammatory conditions, including neuroinflammatory conditions such as multiple sclerosis and spinal cord injury based on the modulation of nerve injury-induced protein-1 (Ninjurin-1) and/or melanoma cell adhesion molecule (MCAM) are disclosed. Methods, and kits useful for the identification and selection of inflammatory cytokine-secreting T cells or precursors thereof, are also disclosed.

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