Use of 8,9-dehydroestrone as an estrogen with neutral...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/565 (2006.01) A61K 31/00 (2006.01) A61K 31/21 (2006.01) A61K 31/56 (2006.01) C07J 1/00 (2006.01) C07J 31/00 (2006.01) C07J 53/00 (2006.01)

Patent

CA 2215655

This invention provides a method of providing estrogen therapy or supplementation in a mammal in need thereof, wherein an elevation in prolactin levels concomitant with said estrogenic supplementation is undesirable in said mammal, which comprises administering an effective amount of 8,9-dehydroestrone or a pharmaceutically acceptable salt of its 3-sulfate ester to said mammal.

La présente invention porte sur une méthode d'oestrogénothérapie ou de supplémentation en oestrogène chez un mammifère qui en a besoin, lorsque l'augmentation concomitante des concentrations de prolactine avec ladite supplémentation en oestrogène n'est pas souhaitable chez ledit mammifère, qui comprend l'administration audit mammifère d'une quantité efficace de 8,9-déshydroestrone ou d'un sel pharmaceutiquement acceptable dont son ester 3-sulfate.

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