C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01)
Patent
CA 2405291
Disclosed herein is a rational, multi-tier approach to the administration of growth factor proteins in the treatment of heart disease. Also disclosed is a method to evaluate the effectiveness of the administration of growth factor proteins comprising the clinical assay of CPK-MB levels in a patient undergoing treatment with growth factor proteins. In addition, there is disclosed a method for treatment of heart disease comprising administration of a therapeutically effective amount of a growth factor protein by oral inhalation therapy.
L'invention concerne une approche multiniveau rationnelle destinée à l'administration de protéines de facteurs de croissance dans le traitement d'une cardiopathie. L'invention concerne également une méthode destinée à évaluer l'efficacité de l'administration de protéines de facteurs de croissance comprenant l'essai clinique de niveaux CPK-MB chez un patient soumis à un traitement aux protéines de facteurs de croissance. L'invention se rapporte en outre à une méthode de traitement d'une cardiopathie consistant à administrer une dose thérapeutiquement efficace d'une protéine d'un facteur de croissance par inhalation orale.
Franco Wayne P.
Ridout & Maybee Llp
LandOfFree
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