A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 38/26 (2006.01) A61K 38/28 (2006.01) A61K 38/51 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61P 3/10 (2006.01) C12N 5/06 (2006.01) C12N 5/08 (2006.01)
Patent
CA 2658678
A composition for the prevention or treatment of type I diabetes in a subject, said composition comprising a fusion protein selected from the group consisting of GLP-1/IgG or variant or fragment thereof and an Ex4/IgG or variant or fragment thereof and an autoimmune suppressor for silencing an autoimmune response against islet beta cells.
La présente invention concerne une composition servant à la prévention ou au traitement du diabète de type 1 chez un sujet, laquelle composition comprend une protéine de fusion sélectionnée dans le groupe comprenant un GLP-1/IgG ou une variante ou un fragment de celui-ci et une Ex4/IgG ou une variante ou un fragment de celle-ci et un suppresseur auto-immun servant au silençage d'une réponse auto-immune contre des cellules bêta des îlots pancréatiques.
Prud'homme Gerald J.
Wang Qinghua
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Wang Qinghua
LandOfFree
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