A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 63/00 (2006.01) A01K 67/00 (2006.01) A01K 67/027 (2006.01) A01K 67/033 (2006.01) A61K 48/00 (2006.01) C07K 14/49 (2006.01) C12N 15/00 (2006.01) C12N 15/85 (2006.01) G01N 33/00 (2006.01) A01N 65/00 (2006.01)
Patent
CA 2403829
Non-human transgenic animals overexpressing PDGF-C and cells thereof have been created. The transgenic animals contain a nucleotide sequence that encodes for platelet derived growth factor C (PDGF-C) or an analog thereof. These animals are useful for studying disease states characterized by overexpression of PDGF- C, as well as useful for evaluating therapies intended to treat such diseases.
Cette invention concerne la création d'animaux transgéniques non humains qui surexpriment le facteur de croissance PDGF-C et des cellules de ce facteur. Ces animaux transgéniques renferment une séquence nucléotidique qui code pour la plaquette dérivée du facteur de croissance C (PDGF-C) ou d'un analogue. Ces animaux sont utiles pour l'étude de cas pathologiques caractérisés par une surexpression de PDGF-C, ainsi que pour l'évaluation de thérapies pour de telles maladies.
Aase Karin
Eriksson Ulf
Li Hong
Li Xuri
Ponten Annica
Aase Karin
Eriksson Ulf
Li Hong
Li Xuri
Ludwig Institute For Cancer Research
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