Il-2 deletion mutants

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/26 (2006.01) A61K 47/48 (2006.01) C07K 14/55 (2006.01)

Patent

CA 2064696

2064696 9102000 PCTABS00003 A mutant IL-2 molecule capable of binding an IL-2 receptor-bearing cell, having a deletion of one to five amino acid residues of IL-2, the deletion resulting in active IL-2 molecules that have increased resistance to proteolysis.

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