Selection of binding-molecules

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07K 1/00 (2006.01) C07K 1/22 (2006.01) C07K 14/00 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2128016

2128016 9314108 PCTABS00024 Methods of designing and producing sequence-specific DNA binding proteins, methods of determining the affinity of a specific binding molecule for a target and products produced by these methods are disclosed. The methods include: forming a reversible bond between a specific binding molecule and the target and determining the susceptibility of the reversible bond to reversal as a measure of the affinity of the binding molecule for the target.

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