3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine...

Details 3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine... 3-(3-pyrimidin-2-ylbenzyl)-1,2,4-triazolo[4,3-b]pyridazine...

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 35/02 (2006.01)

Patent

CA 2728194

Compounds of the formula (I) in which R1, R2, R3, R3', R4 are each as defined in claim 1 are inhibitors of tyrosine kinases, especially of Met kinase, and can be used for treatment of tumours among other uses.

L'invention porte sur des composés de formule (I) dans laquelle R1, R2, R3, R3', R4 ont les significations données dans la revendication 1, composés qui sont des inhibiteurs des tyrosine-kinases, en particulier de la kinase MET, et qui peuvent être utilisés notamment pour le traitement de tumeurs.

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