Production of protein-polysaccharide conjugates

A - Human Necessities – 23 – J

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A23J 3/08 (2006.01) A61K 35/20 (2006.01) C07D 277/54 (2006.01) C07H 3/06 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2711789

The present invention provides novel compositions and methods for producing protein-polysaccharide conjugates in aqueous solutions. Also provided are methods for limiting the Maillard reaction to the very initial stage, the formation of the Schiff base. Provided are methods to obtain a simple product of Schiff base with white color, and compositions obtained using the methods of the present invention.

Cette invention concerne de nouvelles compositions et des procédés pour produire des conjugués protéine-polysaccharide en solutions aqueuses. Elle concerne également des procédés pour limiter la réaction de Maillard à la seule étape initiale, à savoir, la formation de la base de Schiff. Des procédés pour obtenir un produit simple du type base de Schiff de couleur blanche, et des compositions obtenues par les procédés selon la présente invention sont décrits.

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