Improved nucleic acid reactions

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) C12Q 1/70 (2006.01)

Patent

CA 2165544

A method of promoting a reaction between a duplex-binding ligand and a duplex nucleic acid molecule, the duplex nucleic acid molecule being formed from a first single strand nucleic acid molecule and a second single strand nucleic acid molecule, under conditions wherein the rate of duplex formation would be substantially less in the absence of the duplex-binding ligand.

L'invention concerne une méthode pour favoriser la réaction entre un ligand se liant à un duplex et une molécule duplex d'acide nucléique, la molécule duplex d'acide nucléique étant formée d'une première molécule d'acide nucléique à simple brin et d'une seconde molécule d'acide nucléique à simple brin, dans des conditions où le taux de formation du duplex serait nettement inférieur en l'absence du ligand se liant au duplex.

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