Method and composition for cancer diagnosis and treatment

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2698400

Methods and compositions for inhibiting the onset of cancer, and cancer diagnosis and treatment are provided. The treatment method comprises inhibiting the level or function of transcriptional positive factor 4 (PC4). Also provided are methods of screening for cancer inhibition agents based on inhibition of PC4 expression or function.

L'invention porte sur des méthodes et compositions inhibant la formation de cancers et en permettant le diagnostic et le traitement. La méthode de traitement consiste à inhiber le niveau ou la fonction du facteur de transcription positif 4(PC4). L'invention porte également sur des méthodes de criblage d'agents inhibiteurs de cancers basées sur l'inhibition de l'expression ou de la fonction du PC4.

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