Process for making fused-ring imidazo-containing compounds

Details Process for making fused-ring imidazo-containing compounds Process for making fused-ring imidazo-containing compounds

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61K 31/5517 (2006.01) A61P 9/00 (2006.01) A61P 29/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01) C07D 243/00 (2006.01) C07D 487/04 (2006.01) C07F 7/08 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2372469

The subject invention involves processes for making fused-ring imidazo- containing compounds having structure (1) by obtaining and cyclizing compounds having structure (2) wherein m, n, R, R1, Q1 and Q2 are as defined herein, -X1 is selected from -C1, -Br, -I, -OH and -COOH, and -SEM is -CH2OCH2CH2-Si(CH3)3.

L'invention concerne des procédés permettant de fabriquer des composés contenant imidazo à cycles condensés présentant la structure (1) par obtention et cyclisation de composés ayant la structure (2), dans laquelle m, n, R, R1, Q1 et Q2 sont tel que définis dans le descriptif, -X1 est choisi parmi Cl, -Br, -I, -OH et COOH, SEM étant -CH¿2?OCH¿2?CH¿2?-Si(CH¿3?)¿3?.

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