C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/505 (2006.01) A61P 15/00 (2006.01)
Patent
CA 2387353
There is provided compounds of formula (I) wherein R1, R2, R3, R4 and X have meanings given in the description, which are useful in the curative and prophylactic treatment of a medical condition for which inhibition of a cyclic guanosine 3',5'-monophosphate phosphodiesterase (e.g. cGMP PDE5) is desired.
L'invention concerne des composés de formule (I) dans laquelle R?1¿, R?2¿, R?3¿, R?4¿ et X ont les significations indiquées dans le descriptif. Ces composés sont utiles dans le traitement curatif et préventif d'une maladie nécessitant l'inhibition d'une guanosine 3',5'-monophosphate phosphodiestérase cyclique (e.g. cGMP PDE5).
Allerton Charlotte Moira Norfor
Barber Christopher Gordon
Maw Graham Nigel
Rawson David James
Pfizer Inc.
Smart & Biggar
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