Guanidinobenzamides as mc4-r agonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 295/20 (2006.01) A61K 31/155 (2006.01) A61K 31/495 (2006.01) A61P 3/00 (2006.01) C07C 279/18 (2006.01) C07D 209/16 (2006.01) C07D 213/40 (2006.01) C07D 213/82 (2006.01) C07D 215/12 (2006.01) C07D 233/54 (2006.01) C07D 241/08 (2006.01) C07D 241/42 (2006.01) C07D 243/08 (2006.01) C07D 295/215 (2006.01) C07D 307/24 (2006.01) C07D 309/14 (2006.01) C07D 333/20 (2006.01) C07D 487/04 (2006.01) C07D 487/08 (2006.01)

Patent

CA 2420694

Compounds of formula (IA) and (IB) are new where the variables R1 through R10 have the values set forth herein. Such compounds have use in treating diseases such as obesity and type II diabetes, and may be provided as pharmaceutical formulations in conjunction with a pharmaceutically acceptable carrier.

L'invention concerne de nouveaux composés qui correspondent aux formules (IA) et (IB), dans lesquelles les variables R1 à R10 ont les significations données dans la description. De tels composés peuvent être utilisés pour traiter des maladies telles que l'obésité et le diabète du type II et peuvent constituer des formulations pharmaceutiques avec un excipient pharmaceutiquement acceptable.

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