Pharmaceutical composition having reduced abuse potential

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/06 (2006.01) A61K 9/52 (2006.01) A61K 31/485 (2006.01) A61K 47/02 (2006.01) A61K 47/30 (2006.01) A61K 47/44 (2006.01) A61P 25/30 (2006.01)

Patent

CA 2626558

A pharmaceutical paste composition comprising an active ingredient such as an addictive substance, a controlled release agent, and a pharmaceutically suitable aqueous or non-aqueous carrier. The composition may comprise one or more of a clay, or an oily, waxy, or fatty substance. The composition may be filled into a capsule or other dispensing device. The composition may reduce dose dumping of an active ingredient. Methods of making and using the composition are also described.

La présente invention concerne une composition pharmaceutique pâteuse qui comprend une matière active telle qu'une substance addictive, un agent de libération contrôlée et un vecteur aqueux ou non aqueux pharmaceutiquement approprié. La composition peut comprendre une ou plusieurs substances parmi une argile ou une substance huileuse, cireuse ou grasse. La composition peut être conditionnée dans une capsule ou dans un autre dispositif d'administration. La composition peut la libération massive d'une matière active. L'invention concerne également des procédés de fabrication et d'utilisation de la composition.

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