1,2,3-triazole derivatives as sigma receptor inhibitors

Details 1,2,3-triazole derivatives as sigma receptor inhibitors 1,2,3-triazole derivatives as sigma receptor inhibitors

C - Chemistry, Metallurgy

07

D

C07D 249/06 (2006.01) A61K 31/4192 (2006.01) A61P 25/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2668996

The invention relates to compounds having pharmacological activity towards the sigma receptor, and more particularly to 1,2,3-triazole derivatives of formula (I) and to processes of preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in therapy and prophylaxis, in particular for the treatment of psychosis or pain.

L'invention concerne l'utilisation de composés présentant une activité pharmacologique envers le récepteur sigma, et plus particulièrement des dérivés de 1,2,3-triazole de formule (I), ainsi que des procédés de préparation desdits composés, des compositions pharmaceutiques les contenant, et leur utilisation en thérapie et en prophylaxie, en particulier dans le traitement de la psychose et de la douleur.

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