1,2-bis(aminomethyl) cyclobutane platinum complexes

Details 1,2-bis(aminomethyl) cyclobutane platinum complexes 1,2-bis(aminomethyl) cyclobutane platinum complexes

C - Chemistry, Metallurgy

07

F

167/119, 260/429

C07F 15/00 (2006.01) A61K 31/295 (2006.01) A61K 31/555 (2006.01)

Patent

CA 1316177

ABSTRACT OF THE DISCLOSURE There are disclosed 1,2-Bis(aminomethyl)cyclobutane- platinum complexes having the general formula Image I ' or Image I'' wherein the radicals R1, R2, R3, R4, R5 and R6 are the same or different and represent hydrogen, C1-C6-alkyl, phenyl, phenyl-C1-C6-alkyl, C1-C6-alkyl which is substituted by halogen, hydroxy, C2-C6-alkanoyloxy or C1-C6-alkoxy, phenyl which is substituted by halogen, hydroxy, C2-C6-alkanoyloxy or C1-C6-alkoxy or phenyl-C1-C6-alkyl which is substituted in the phenyl moiety by halogen, hydroxy, C2-C6-alkanoyloxy or C1-C6-alkoxy and X represents the equivalent of a physiologically acceptable anion or X represents a water molecule and in this case the existing positive charge of the platinum atom is also neutralized by a physiologically acceptable anion, and salts thereof. These complexes have anti-tumour activity.

587664

Affiliated with

Also associated with

Rating

1,2-bis(aminomethyl) cyclobutane platinum complexes does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1,2-bis(aminomethyl) cyclobutane platinum complexes, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1,2-bis(aminomethyl) cyclobutane platinum complexes will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1301572