1,2-dihydropyrido(3,4-b)pyrazines as fungicides

Details 1,2-dihydropyrido(3,4-b)pyrazines as fungicides 1,2-dihydropyrido(3,4-b)pyrazines as fungicides

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2103457

2103457 9220680 PCTABS00017 1,2-dihydropyrido[3,4-b]pyrazines are provided which possess antimitotic activity. The compounds have structure (I) wherein R is a lower alkyl group and OR1 is a member selected from the group consisting of aryl-alkyl ethers having from seven to about 20 carbon atoms, alkyl carbamates having from one to about 12 carbon atoms, the alkyl portion of which may be substituted with a halogen atom, e.g., chlorine, fluorine, bromine or iodine; aryl-alkyl carbamates having from about seven to about 20 carbon atoms, aryl carbamates having from about six to about 20 carbon atoms, aryl-alkyl esters having from about seven to about 20 carbon atoms, aryl esters having from about six to about 20 carbon atoms, alkylthiocarbamates having from about one to about 12 carbon atoms, aryl-alkylthiocarbamates having from about seven to about 20 carbon atoms, and arylthiocarbamates having from about six to about 20 carbon atoms.

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