1,4-benzoxazine compounds and derivatives thereof as...

C - Chemistry – Metallurgy – 07 – D

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C07D 265/36 (2006.01) A61K 31/538 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2734305

The present invention includes compositions and methods for inhibiting kinase activity to protect against neurodegeneration including diseases such as Alzheimer's disease, Parkinson's disease, or Huntington's disease, and conditions such as ischemic stroke comprising the step of providing the subject with a therapeutically affective amount of 1,4- benzoxazine compounds and derivatives thereof.

L'invention concerne des compositions et procédés pour inhiber une activité kinase afin de protéger à l'encontre d'une neurodégénération, y compris des maladies comme la maladie d'Alzheimer, la maladie de Parkinson, ou la maladie d'Huntington, et des états comme un accident ischémique, comprenant l'étape consistant à fournir au sujet une quantité thérapeutiquement efficace de composés de 1,4-benzoxazine, et de dérivés de ceux-ci.

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