1,4-dihydropyridine derivative, process for preparing the...

Details 1,4-dihydropyridine derivative, process for preparing the... 1,4-dihydropyridine derivative, process for preparing the...

C - Chemistry, Metallurgy

07

D

167/228, 260/278

C07D 211/90 (2006.01) A61K 31/44 (2006.01) C07D 401/06 (2006.01)

Patent

CA 2022194

Abstract of the Disclosure A 1,4-dihydropyridine derivative having the formula (I): Image (I) wherein X is oxygen atom or nitrogen atom; when X is oxygen atom, R1 is hydrogen atom, a lower alkyl group, a lower cycloalkyl group, a lower alkenyl group or magnesium atom, when X is nitrogen atom, X-R1 group is NH2, NHR1, NR1'R1'' or Image in which R1' is a lower alkyl group or a lower alkoxyalkyl group, R1'' is a lower alkyl group and n is an integer of 2 to 6; R2 is a lower alkyl group, a lower cycloalkyl group or a lower alkoxyalkyl group and R3 is a lower alkyl group, formyl group, dimethoxymethyl group, cyano group or amino group, when X is oxygen atom and R1 is hydrogen atom or magnesium atom, R3 is methyl group, when X is nitrogen atom, R3 is methyl group, or a pharmaceutically acceptable salt thereof, some processes for preparing the same and a pharmaceutical composition containing the same. According to the present invention, a superior cerebral function improver can be provided.

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