1,4-dihydropyridine derivatives and processes for preparing...

Details 1,4-dihydropyridine derivatives and processes for preparing... 1,4-dihydropyridine derivatives and processes for preparing...

C - Chemistry, Metallurgy

07

D

260/294.2

C07D 211/90 (2006.01)

Patent

CA 1176255

ABSTRACT OF THE DISCLOSURE Novel 1, 4-dihydropyridine derivatives or the pharmacologically acceptable salts thereof represented by the following general formula (I), and process for preparing the same Image (I) wherein R1 is dialkoxyalkyl, formyl, formylalkyl, or hydroxy- alkyl; R2 represents alkoxyalkyl, alkenyloxyalkyl, aryloxy- alkyl, or aralkyloxyalkyl; R3 denotes alkyl, haloalkyl, alkoxyalkyl, alkenyloxyalkyl, aryloxyalkyl, aralkyloxyalkyl, or N,N-di-substituted aminoalkyl (the substituents are the same or different alkyl, aralkyl, or aryl); R4 is alkyl, dialkoxyalkyl, formyl, formylalkyl, or hydroxyalkyl, and R5 is ortho-, meta-, or paranitro. The compounds of the present invention possess vaso-dilation activities and hypotensive activities, and are very useful medicines for the blood circulatory system.

401133

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