1,4-dihydropyridine-fused heterocycles, process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/14 (2006.01) A61K 31/4162 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2615700

1,4-Dihydropyridine-fused heterocycles, process for preparing the same, use and compositions containing them. The invention is about substituted dihydropyridine-fused heterocycles useful for the treatment of cancer disease, especially for preventing cancerous cells to divide. These compounds act as inhibitors of Aurora A and/or B kinases. Formula (I).

L'invention concerne des hétérocycles fusionnés de 1,4-dihydropyridine, un procédé pour préparer ceux-ci, ainsi que leurs utilisations et des compositions les contenant. L'invention concerne des hétérocycles fusionnés de dihydropyridine utiles pour traiter un cancer, en particulier pour éviter une division de cellules cancéreuses. Ces composés servent d'inhibiteurs aux kinases Aurora A et/ou B. Formule (I).

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