1,4-disubstituted piperazine derivatives, pharmaceutical...

Details 1,4-disubstituted piperazine derivatives, pharmaceutical... 1,4-disubstituted piperazine derivatives, pharmaceutical...

C - Chemistry, Metallurgy

07

D

167/223, 260/267

C07D 295/092 (2006.01) A61K 31/495 (2006.01) C07D 295/088 (2006.01)

Patent

CA 1277986

1,4-DISUBSTITUTED PIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR PREPARING SAME ABSTRACT The invention relates to novel 1,4-disubsti- tuted piperazine derivatives of the general formula (I), pharmaceutically acceptable acid addition salts thereof, pharmaceutical compositions containing them and a process for their preparation. In the general formula (I) Image (I) R1 and R2 are the same or different and stand for hydrogen or halogen or a lower alkyl, trihalomethyl or lower alkoxy group. The compounds of the general formula (I) are therapeutically useful for the treatment of diseases arising from a hypofunction of the dopaminergic system.

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