1,5-diazocine derivatives and process for the preparation...

C - Chemistry – Metallurgy – 07 – D

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260/237.75

C07D 487/14 (2006.01) C07D 471/14 (2006.01)

Patent

CA 1040199

ABSTRACT OF THE DISCLOSURE This invention relates to compounds of the general formula I and salts thereof: Image I and acid addition salts thereof wherein R1, R2, R3 and R4 are the same or different and each stands for a hydrogen atom or alkoxy group of 1 to 4 carbon atoms. These compounds are prepared by reacting a compound of the formula II: Image II or a tautomer thereof wherein the various symbols are as previously defined with formaldehyde or a compound capable of releasing formaldehyde e.g. paraformaldehyde. The compounds of formula I are useful intermediates in the preparation of therapeutically valuable compounds.

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