1-¬6-(2'-substituted-5',6',7',8'-tetrahydro-4'-oxo-...

Details 1-¬6-(2'-substituted-5',6',7',8'-tetrahydro-4'-oxo-... 1-¬6-(2'-substituted-5',6',7',8'-tetrahydro-4'-oxo-...

C - Chemistry, Metallurgy

07

D

167/218, 260/254

C07D 401/00 (2006.01) A61K 31/435 (2006.01) A61K 31/505 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 417/14 (2006.01)

Patent

CA 1266649

Abstract The invention relates to new 1-[6-(2'- -substituted-5',6',7',8'-tetrahydro-4'-oxo-quinazolino)]- -3,4-dihydro-6,7-disubstituted-isoquinoline derivatives of the formula (I) Image (I) wherein R1 and R2 each independently represents hydroxyl or alkoxy having from 1 to 6 carbon atoms, R3 is alkyl having from 1 to 6 carbon atoms, optionally substituted phenyl, optionally substituted alkylphenyl having from 1 to 4 carbon atoms in the alkyl moiety or an optionally substituted heterocyclic group, and acid addition and quaternary salts thereof. Compounds of the formula (I) are pharmaceutical- ly active, in particular show spasmolytic, analgesic, antipyretic activity and have a protecting effect in acute alcoholic intoxication.

478872

Affiliated with

Also associated with

Rating

1-¬6-(2'-substituted-5',6',7',8'-tetrahydro-4'-oxo-... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 1-¬6-(2'-substituted-5',6',7',8'-tetrahydro-4'-oxo-..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 1-¬6-(2'-substituted-5',6',7',8'-tetrahydro-4'-oxo-... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1177080