C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/273
C07D 471/04 (2006.01)
Patent
CA 1125757
ABSTRACT OF THE DISCLOSURE: This invention relates to the novel 1,6-naphthyridine derivatives useful as antidinic and/or cerebral circulation improver, such novel derivatives being represented by the follow- ing general formula: Image (I) (wherein R is a C2-10 alkyl which may have hydroxyl, lower alkyl- carbonyl, lower alkyloxycarbonyl or phenoxy as a substituent; a C2-10 unsaturated aliphatic hydrocarbon group having unsaturated double bond(s); a phenyl-lower alkyl which may have halogen, lower alkyl, lower alkoxy or lower alkylthio as substituent(s) attached to the phenyl ring; a cinnamyl which may have halogen, nitro, lower alkyl or lower alkoxy as substituent(s) attached to the phenyl ring; propargyl; 1-naphthylmethyl; 2-thenyl; cyclo- hexenyl; a cycloalkyl-lower alkyl with a 3- to 6-membered ring; ?(C2-4 alkylene); ?(butenylene), or diphenylmethyl, and in case two alkoxyl groups are present attached to the phenyl ring, they may be bonded to form a ring) and salt thereof.
337711
Ichikawa Yuh-Ichiro
Ishikawa Michio
Miyazaki Hiroshi
Sakamoto Takao
Shiozawa Akira
Borden Ladner Gervais Llp
Nippon Kayaku Kabushiki Kaisha
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