1-amido-4-phenyl-4-benzyloxymethyl-piperidine derivatives...

Details 1-amido-4-phenyl-4-benzyloxymethyl-piperidine derivatives... 1-amido-4-phenyl-4-benzyloxymethyl-piperidine derivatives...

C - Chemistry, Metallurgy

07

D

C07D 211/98 (2006.01) A61K 31/445 (2006.01) A61K 31/496 (2006.01) A61K 31/5377 (2006.01) C07D 401/04 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2490463

Disclosed are NK1 antagonists having the formula: Also disclosed are uses of compounds of formula (I) for the manufacture of a medicament for treating a number of physiological disorders, symptoms or diseases, including emesis, depression, anxiety and cough.

L'invention concerne des antagonistes de NK¿1? ayant la formule (I). L'invention concerne également les utilisations de composés de la formule (I) dans la fabrication d'un médicament destiné au traitement d'un certain nombre de troubles, symptômes ou maladies physiologiques parmi lesquels les vomissements, la dépression, l'angoisse et la toux.

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