1-n-(.alpha.-hydroxy-.omega.-aminoalkanoyl) derivatives of...

C - Chemistry – Metallurgy – 07 – H

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C07H 15/00 (2006.01) C07H 15/236 (2006.01)

Patent

CA 1175816

New 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl) derivatives of 5,3',4'-trideoxy- or 5,3',4'-trideoxy-6'-N-methyl- or 5,3',4',6"-tetradeoxy-kanamycin B and production thereof ABSTRACT OF THE DISCLOSURE New antibacterial compounds are provided, including a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4'-trideoxykanamycin B; a 1-N-(.alpha.-hydroxy-.omega.-aminoalkanoyl)-5,3',4',6"-tetra- deoxykanamycin B; and a 1-N-(a-hydroxy-.omega.-aminoalkanoyl)- 5,3',4'-trideoxy-6'-N-methylkanamycin B; as well as 5,3',4',6"-tetradeoxykanamycin B and 5,3',4'-trideoxy- 6'-N-methylkanamycin B.

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