1ó,26 dihydroxy-d-homo-vitamin d3

Details 1ó,26 dihydroxy-d-homo-vitamin d3 1ó,26 dihydroxy-d-homo-vitamin d3

C - Chemistry, Metallurgy

07

C

C07C 401/00 (2006.01) A61K 31/045 (2006.01) A61K 31/59 (2006.01) A61P 17/00 (2006.01) A61P 19/10 (2006.01) A61P 35/00 (2006.01) C07C 39/00 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2188634

A 1.alpha.,26-dihydroxy-D-homo-vitamin D3 of formula I is described: Image Formula I The systematic nomenclature of the compound of formula I is (1R,3S)-5-[(Z)-2- [(E)-(4aR,5R,8aR)-5-[(R)-5-Hydroxy-1,5-dimethyl-hexyl]-4a-methyl-octahydro- naphtalen-1-ylidene]-ethylidene]-4-methylene-cyclohexane-1,3-diol. A process for the preparation of the compound of formula I, pharmaceutical compositions containing the compound of formula I, and the use of the compound of formula I for the treatment of vitamin D dependent disorders, and for the manufacture of pharmaceutical compositions for the treatment of vitamin D dependent disorders is described.

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