2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine...

Details 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine... 2-(2-hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine...

C - Chemistry, Metallurgy

07

D

C07D 235/18 (2006.01) C07D 235/12 (2006.01) C07D 235/16 (2006.01) C07D 401/12 (2006.01) C07D 403/10 (2006.01) C07D 407/12 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2507707

The present invention relates to novel compound of Formula I inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.

L'invention concerne des nouveaux inhibiteurs des facteurs VIIa, IXa, Xa, XIa, en particulier du facteur VIIa, des compositions pharmaceutiques contenant ces inhibiteurs, et des procédés d'utilisation de ces derniers pour le traitement ou la prévention des troubles thromboemboliques, du cancer ou de la polyarthrite rhumatoïde. L'invention concerne également des procédés de préparation desdits inhibiteurs.

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