2,3,5-trisubstituted pyridines as inhibitors of...

C - Chemistry – Metallurgy – 07 – D

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C07D 213/64 (2006.01) A61K 31/44 (2006.01) C07D 213/61 (2006.01) C07D 213/70 (2006.01)

Patent

CA 2301742

The invention encompasses the novel compound of Formula (I) as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non- toxic therapeutically effective amount of a compound of Formula (I). The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula (I).

L'invention concerne un nouveau composé de formule (I), ainsi qu'une méthode permettant de traiter les maladies ayant pour médiateur la cyclo-oxygénase 2, qui consiste à administrer à un patient ayant besoin dudit traitement une quantité, efficace sur le plan thérapeutique et non toxique, d'un composé de formule (I). L'invention concerne également certaines compositions pharmaceutiques destinées au traitement des maladies ayant pour médiateur la cyclo-oxygénase 2 et renfermant des composés de formule (I).

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