2, 3-dihydrobenzo[1, 4] dioxin-2-ylmethyl derivatives as...

Details 2, 3-dihydrobenzo[1, 4] dioxin-2-ylmethyl derivatives as... 2, 3-dihydrobenzo[1, 4] dioxin-2-ylmethyl derivatives as...

C - Chemistry, Metallurgy

07

D

C07D 405/06 (2006.01) A61K 31/357 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2693804

Compounds of formula (I), wherein X, Z, R1-R4, and m are as defined in the claims, exhibit alpha2C antagonistic activity and are thus useful for the treatment of diseases and conditions of the peripheric system and the central nervous system (CNS).

La présente invention concerne des composés de formule (I). Dans ladite formule, X, Z, R1-R4 et m sont tels que définis dans les revendications. Lesdits composés présentent une activité antagoniste envers les alpha2C, et peuvent par conséquent être utilisés pour traiter des maladies et des états du système nerveux périphérique et du système nerveux central (SNC).

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