2,4,8-trisubstituted-8h-pyrido[2,3-d}pyrimidin-7-one compounds

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/505 (2006.01) A61P 19/00 (2006.01) A61P 31/00 (2006.01) C07D 239/02 (2006.01) C07D 239/46 (2006.01) C07D 471/02 (2006.01)

Patent

CA 2426654

Novel substituted 2,4,8-trisubstituted -8H-pyrido[2,3-d]pyrimidin-7-one compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.

La présente invention concerne des nouveaux composés disubstitués 2, 4 et trisubstitués 8 -8H-pyrido[2,3-d]pyrimidine-7-ones, ainsi que des compositions pouvant être utilisés dans une thérapie en tant qu'inhibiteurs de la kinase CSBP/p38.

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