2, 4 -di (arylaminio) -pyrimidine-5-carboxamide compounds as...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 239/48 (2006.01) A61K 31/505 (2006.01) A61P 9/00 (2006.01) A61P 35/00 (2006.01) A61P 37/00 (2006.01)

Patent

CA 2657260

Disclosed are pyrimidine derivatives of formula (I) exhibiting JAK-3 and JAK-2 kinase inhibiting activities. wherein R1 ,R2, R3 and R4 are as described herein.

L'invention concerne des dérivés du pyrimidine de formule I présentant des activités inhibitrices de JAK3 et des JAK-3 kinases, où R1, R2, R3 et R4 sont tels que décrits présentement.

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