2,6-di-t-butyl-4-[ (dimethyl-4-methoxyphenylsilyl)...

C - Chemistry – Metallurgy – 07 – F

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C07F 7/08 (2006.01) A61K 31/695 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2295232

This invention relates to the compounds of 2,6-di-t-butyl-4- [(dimethyl-4- methoxyphenylsilyl)-methyloxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2- methoxyphenylsilyl)methyloxy]phenol, polymorphs thereof and their pharmaceutically acceptable salts, useful as antiatherosclerotic agents.

La présente invention concerne les composés de 2,6-di-t-Butyl-4- [(diméthyl-4- méthoxyphénylsilyl)-méthyloxy]phénol et 2,6-di-t-butyl-4-[(diméthyl-2-méthoxyphénylsilyl)méthyloxy]phénol, les polymorphes de ces composés ainsi que leurs sels pharmaceutiquement acceptables; ces composés étant des agents utiles pour combattre l'athérosclérose.

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