C - Chemistry – Metallurgy – 07 – F
Patent
C - Chemistry, Metallurgy
07
F
C07F 7/08 (2006.01) A61K 31/695 (2006.01) A61P 9/10 (2006.01)
Patent
CA 2295232
This invention relates to the compounds of 2,6-di-t-butyl-4- [(dimethyl-4- methoxyphenylsilyl)-methyloxy]phenol and 2,6-di-t-butyl-4-[(dimethyl-2- methoxyphenylsilyl)methyloxy]phenol, polymorphs thereof and their pharmaceutically acceptable salts, useful as antiatherosclerotic agents.
La présente invention concerne les composés de 2,6-di-t-Butyl-4- [(diméthyl-4- méthoxyphénylsilyl)-méthyloxy]phénol et 2,6-di-t-butyl-4-[(diméthyl-2-méthoxyphénylsilyl)méthyloxy]phénol, les polymorphes de ces composés ainsi que leurs sels pharmaceutiquement acceptables; ces composés étant des agents utiles pour combattre l'athérosclérose.
Chen Kim S.
Edwards Michael L.
Matt James E. Jr.
Parker Roger A.
Vaal Mark J.
Aventis Pharmaceuticals Inc.
Hoechst Marion Roussel Inc.
Osler Hoskin & Harcourt Llp
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