2 , 6-naphthyridine derivatives as protein kinase modulators

Details 2 , 6-naphthyridine derivatives as protein kinase modulators 2 , 6-naphthyridine derivatives as protein kinase modulators

C - Chemistry, Metallurgy

07

D

C07D 471/04 (2006.01) A61K 31/4745 (2006.01)

Patent

CA 2682339

The present invention relates to novel organic compounds comprising a naphthyridine which may be mediators of a selective subset of kinases belonging to the AGC kinase family, such as for example PKC, PKD, PKN-1/2, CDK-9, MRCK-beat, PASK, PRKX, ROCK-I/II or mediators of other kinases, the selectivity of which would be depending on the structural variation thereof.

L'invention concerne de nouveaux composés organiques contenant une naphthyridine, pouvant servir de médiateurs d'un sous-ensemble sélectif de kinases appartenant à la famille des kinases AGC, telles que PKC, PKD, PKN-1/2, CDK-9, MRCK-beat, PASK, PRKX, ROCK-I/II, ou de médiateurs d'autres kinases dont la sélectivité dépend de leur variation structurelle.

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