2,7-substituted octahydro-1h-pyrido¬1,2-a|pyrazine...

Details 2,7-substituted octahydro-1h-pyrido¬1,2-a|pyrazine... 2,7-substituted octahydro-1h-pyrido¬1,2-a|pyrazine...

A - Human Necessities

61

K

A61K 31/497 (2006.01) A61K 31/495 (2006.01) A61K 31/4985 (2006.01) A61K 31/505 (2006.01)

Patent

CA 2314867

Substituted pyrido[1,2-a]pyrazines of general formula 1; wherein Ar and Ar1 represent various carbocyclic and heterocyclic aromatic rings; A represents O, S, SO, SO2, CHOH, C=O, or -(CR3R4); and n is 0-2, as well as precursors thereto, are ligands for dopamine receptor subtypes and serotonin (5HT) within the body and are therefore useful in the treatment of disorders of the dopamine and serotonin systems: (see formula I)

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