C - Chemistry – Metallurgy – 07 – C
Patent
C - Chemistry, Metallurgy
07
C
C07C 257/14 (2006.01) C07C 229/30 (2006.01) C07C 259/14 (2006.01) C07C 271/22 (2006.01) C07D 271/06 (2006.01) C07D 271/07 (2006.01) C07D 413/06 (2006.01) C07F 7/18 (2006.01)
Patent
CA 2421504
The present invention relates to 2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives and their use in therapy, in particular their use as nitric oxide synthase inhibitors. In one embodiment of the invention, there is a compound of Formula I: (see formula I) or a pharmaceutically acceptable salt thereof, wherein: R1 is hydrogen, halo, or C1-C5 alkyl, said C1-C5 alkyl optionally substituted by halo or alkoxy, said alkoxy optionally substituted by one or more halo; R2 is hydrogen, halo, or C1-C5 alkyl, said C1-C5 alkyl optionally substituted by halo or alkoxy, said alkoxy optionally substituted by one or more halo; and R3 is C1-C5 alkyl, said C1-C5 alkyl optionally substituted by halo or alkoxy, said alkoxy optionally substituted by one or more halo.
La présente invention concerne des dérivés d'acide 2-amino-2-alkyl-5 hepténoïque et heptynoïque, et leur utilisation dans des thérapies, notamment comme inhibiteurs de monoxyde d'azote synthase.
Bergmanis Arija A.
Grapperhaus Margaret
Hagen Timothy J.
Hallinan E. Ann
Hansen Donald Jr.
Pharmacia Corporation
Smart & Biggar
LandOfFree
2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-amino-2-alkyl-5 heptenoic and heptynoic acid derivatives... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1919183