2 -aminopyridine analogs as glucokinase activators

Details 2 -aminopyridine analogs as glucokinase activators 2 -aminopyridine analogs as glucokinase activators

C - Chemistry, Metallurgy

07

D

C07D 417/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 491/04 (2006.01) C07D 495/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01)

Patent

CA 2647208

Provided are compounds of formula I that are useful in the treatment and/or prevention of diseases mediated by deficient levels of glucokinase activity, such as diabetes meilitus. Also provided are methods of treating or preventing diseases and disorders characterized by underactivity of glucokinase or which can be treated by activating glucokinase.

L'invention concerne des composés qui sont utiles dans le traitement et/ou la prévention de maladies médiées par des niveaux insuffisants d'activité de glucokinase, par exemple le diabète sucré. Elle concerne également des méthodes de traitement ou de prévention de maladies et de troubles caractérisés par une sous-activité de la glucokinase ou qui peuvent être traités en activant la glucokinase.

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