C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/506 (2006.01) C07D 405/14 (2006.01) C07D 471/04 (2006.01) C07D 487/08 (2006.01) C07D 487/10 (2006.01)
Patent
CA 2678077
2-Aminopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
La présente invention concerne des composés de 2-aminopyrimidine utiles en tant que modulateurs du récepteur H4. De tels composés peuvent être utilisés dans des compostions pharmaceutiques et des procédé de traitement d'états morbides, de troubles, et de conditions liés à l'activité du récepteur H4, tels que l'allergie, l'asthme, des maladies auto-immunes, et de prurit.
Cai Hui
Chavez Frank
Edwards James P.
Fitzgerald Anne E.
Liu Jing
Janssen Pharmaceutica N.v.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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