2.beta.-substituted-methyl-penicillanic acid derivatives,...

Details 2.beta.-substituted-methyl-penicillanic acid derivatives,... 2.beta.-substituted-methyl-penicillanic acid derivatives,...

C - Chemistry, Metallurgy

07

D

260/111, 167/188

C07D 499/00 (2006.01) A61K 31/43 (2006.01) C07F 7/10 (2006.01)

Patent

CA 1299566

Abstract Disclosed are 2.beta.-substituted-methylpenicillanic acid compounds of the formula Image (I) wherein n is 0, 1 or.2; and Image is monocyclic or bicyclic heterocyclic ring group which has 2 to 4 nitrogen atoms as hetero atom in its ring structure and which may be optionally substituted with alkyl, alkoxycarbonyl, phenyl, formyl or benzyloxycarbonyl optionally having alkyl, nitro or a halogen atom on the benzene ring, with the proviso that said heterocyclic ring group is not 1,2,3-triazol-1-yl; or salts or esters thereof. These compounds are useful as .beta.-lactamase inhibitor.

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