2- [ isoquinolin-s - carbonyl ) amino] -propionic acid...

Details 2- [ isoquinolin-s - carbonyl ) amino] -propionic acid... 2- [ isoquinolin-s - carbonyl ) amino] -propionic acid...

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/4725 (2006.01) A61P 7/02 (2006.01) A61P 9/00 (2006.01) C07D 217/26 (2006.01) C07D 407/12 (2006.01)

Patent

CA 2599808

This invention provides aryl and heteroaryl compounds of formula (X). The compounds of the invention may be useful as antagonists, or partial antagonist of factor IX and/or factor Xl and thus, may be used to inhibit the intrinsic pathway of blood coagulation. Formula (X) wherein R102 is selected from the group consisting of -C(O)OH, -C(O)OCH3, -C(O)O-t-butyl, -C(O)NH-OCH2-phenyl, C(O)NHOH, and -C(O)NHSO2CH3; and wherein R101 .R103,R104 and Y are as defined herein.

La présente invention a trait à des composés aryles et hétéroaryles de formule (X), dans laquelle: R102 est choisi parmi le groupe constitué de -C(O)OH, -C(O)OCH3, -C(O)O-t-butyle, -C(O)NH-OCH2-phenyle, C(O)NHOH, et -C(O)NHSO2CH3; et dans laquelle R101 .R103,R104 et Y sont tels que définis dans la description. Les composés de l'invention peuvent être utiles en tant qu'antagonistes, ou antagonistes partiels du facteur IX et/ou du facteur XI et donc, peuvent être utilisés pour l'inhibition de la voie intrinsèque de la coagulation sanguine.

Affiliated with

Also associated with

Rating

2- [ isoquinolin-s - carbonyl ) amino] -propionic acid... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2- [ isoquinolin-s - carbonyl ) amino] -propionic acid..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2- [ isoquinolin-s - carbonyl ) amino] -propionic acid... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1795279