3-(2-aminoethyl)-4-¬3-(trifluoromethyl)benzoyl|-3,...

Details 3-(2-aminoethyl)-4-¬3-(trifluoromethyl)benzoyl|-3,... 3-(2-aminoethyl)-4-¬3-(trifluoromethyl)benzoyl|-3,...

C - Chemistry, Metallurgy

07

D

C07D 265/36 (2006.01) A61K 31/535 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01) C07D 471/04 (2006.01) C07D 495/04 (2006.01)

Patent

CA 2141728

Compounds of the general formula (I) (I) Image wherein R1 represents a hydrogen, fluorine or chlorine atom or a methyl, C1-C3 alkoxy or nitro group; R3 represents a hydrogen atom or a C1-C3 alkyl group; R4 represents a 2,3-dihydro-1H-inden-2-yl, 2,3-dihydro-1H- inden-1-yl or 1,2,3,4-tetrahydronaphthalen-1-yl group; or alternatively R3 and R4 complete, with the nitrogen atom to which they are attached, a 1,2,3,4-tetrahydro- 9H-pyrido[3,4-b]indol-2-yl, 1,2,3,4-tetrahydro-9H- pyrido[4,3-b]indol-3-yl, 4,5,6,7-tetrahydrothieno[2,3- c]pyrid-6-yl, 4,5,6,7-tetrahydrothieno[3,2-c]pyrid-6-yl or 2,3-dihydro-1H-isoindol-2-yl group; are useful for the treatment and prevention of cerebral disorders.

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