3,3', 4,4'-tetrahydroxy-2,2' -bipyridine-n,n' -dioxides for...

Details 3,3', 4,4'-tetrahydroxy-2,2' -bipyridine-n,n' -dioxides for... 3,3', 4,4'-tetrahydroxy-2,2' -bipyridine-n,n' -dioxides for...

A - Human Necessities

61

K

A61K 31/444 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2736322

Methods are provided of treating renal cancer by administration of certain 3,31,4,4'- tetrahydroxy-2,2'-bipyridine-N,N'-dioxide compounds, especially 3,3',4,4'-tetrahydroxy-2,2'-bipyridine-N,N'-dioxide (Orellanine), using particular administration protocols and dosing regimens, as well as pharmaceutical compositions suitable for use in the treatment methods that are provided.

Linvention concerne des méthodes pour traiter le cancer des reins par administration de certains composés de 3,3',4,4'- tétrahydroxy-2,2'-bipyridine-N,N'-dioxyde, et en particulier 3,3',4,4'-tétrahydroxy-2,2'-bipyridine-N,N'-dioxyde (Orellanine), au moyen de protocoles dadministration et de schémas posologiques particuliers ainsi que des compositions pharmaceutiques appropriées pour être utilisées dans les méthodes de traitement précitées.

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