3,4-diarylpyrazoles as protein kinase inhibitors

Details 3,4-diarylpyrazoles as protein kinase inhibitors 3,4-diarylpyrazoles as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 401/04 (2006.01) A61K 31/4439 (2006.01) A61P 35/00 (2006.01) C07D 403/04 (2006.01) C07D 407/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2731146

3,4-diarylpyrazole derivatives of formula (I) as defined in the specification, and pharmaceutically acceptable salts thereof, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be useful, in therapy, in the treatment of diseases associated with a disregulated protein kinase activity, like cancer.

Cette invention concerne des dérivés du 3,4-diarylpyrazole de formule (I) tels que définis dans la description, et leurs sels pharmaceutiquement acceptables, leur procédé de préparation et des compositions pharmaceutiques les contenant; les composés de linvention peuvent être utilisés dans le traitement des maladies associées avec un dérèglement de lactivité de la protéine kinase, comme le cancer.

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