(3-and/or 4)-(di-or monomethyl)-5-(pyridinyl or...

Details (3-and/or 4)-(di-or monomethyl)-5-(pyridinyl or... (3-and/or 4)-(di-or monomethyl)-5-(pyridinyl or...

C - Chemistry, Metallurgy

07

D

260/294.2, 260/2

C07D 213/64 (2006.01) C07D 401/04 (2006.01)

Patent

CA 1195981

ABSTRACT OF THE DISCLOSURE 3-R1-4-R2-5-Q-6-R-2(1H)-pyridinones (I), where R1 and R2 are each hydrogen or methyl, R is lower-alkyl, and Q is 4(or 3)-hydroxyphenyl, 4(or 3)-methoxyphenyl, 4(or 3)-pyridinyl or 4(or 3)-pyridinyl having one or two lower-alkyl substituents, or acid-addition salts thereof when Q is a pyridinyl substituent, and their preparation are shown. Also shown and claimed is the cardiotonic use of I where Q is 4(or 3)-hydroxyphenyl, 4(or 3) -pyridinyl or 4(or 3)-pyridinyl having one or two lower-alkyl substituents, and at least one of R1 and R2 is methyl.

441534

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