3-aryloxy and 3-heteroaryloxy substituted benzo(b)...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 409/12 (2006.01) A61K 31/41 (2006.01) A61P 35/00 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2527576

The present invention provides benzo[b]thiophenes of Formula (I), wherein R1, R2, R3, R4, R5, and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I).

La présente invention concerne des benzo[b]thiophènes de formule (I), dans laquelle R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, et L ont n'importe laquelle des valeurs définies à cet effet dans la description, ainsi que leurs sels pharmaceutiquement acceptables qui sont utiles comme agents pour traiter des maladies et des affections, et notamment des maladies inflammatoires, des maladies cardio-vasculaires, et des cancers. L'invention concerne également des compositions pharmaceutiques contenant un ou plusieurs composés de la formule (I) .

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